Secretory IgA faces defense mechanism in intestines
Secretory IgA from faeces or stool.
For the collection of IgA (secretory) a normal collection tube of stool is needed.
A good parameter for determining immunity is the secretory IgA.
An abnormal result, i.e. too much or too little secretory IgA, indicates that the defence mechanism of the intestines is functioning insufficiently.
Immunoglobulins play an important role in the body's defense. They protect the body from numerous organisms. Immunoglobulin A (IgA) circulates in the blood and protects against invasion by bacteria, viruses and parasites. Secretory IgA (sIgA) defends the mucous membranes and stimulates the growth and adhesion of beneficial bacteria.
- The correct content of sIgA indicates a good resistance. In case of contact with bacterial substances, the immune system is stimulated to produce extra sIgA.
- An increase often indicates an infection.
- With low sIgA levels there is a decrease in resistance and you have more often inflammations of the mucous membrane, nose and throat, bowel or bladder. Children have more frequent colds. In the Netherlands, 1 in 20 to 50 people with bowel complaints has low sIgA values. A shortage of sIgA can have numerous causes, including a congenital defect, gluten intolerance or stress (especially in the elderly).
This test is also part of the intestinal health screening.