Virulent factors intestinal biome

This RP stool test indicates whether harmful substances made by certain gut bacteria are present in the gut.

The five harmful substances looked at are:

• haemolysin
• urease
• gelatinase
• catalase
• coagulase

If one or more of these substances are present, it means that the immune system cannot perform its function properly. Then, with the right therapy, it is possible to ensure that these substances no longer occur in the intestines by removing the bacteria that make these substances.

While performing this test, the extent to which the intestinal flora is capable of exerting harmful effects is examined. This examination is important in chronic diseases and recurring symptoms of a condition when it already seemed cured (recurrence). Virulent factors do not occur in a healthy and thus balanced intestinal flora.
The following factors are tested for:

• coagulase; an enzyme that speeds up blood clotting
• gelatinase; an enzyme that liquefies gelatin and is found in both bacteria and fungi. It breaks down insulin which can disrupt sugar metabolism. In addition, the enzyme appears to have a negative effect on long-term complications of diabetes.
• haemolysis; bacteria can also be responsible for blood decomposition or breaking down erythrocytes (red blood cells).
• catalase; a converting enzyme that plays a role in protecting cells from free radicals. Catalase is an enzyme found in the peroxisomes of eukaryotic cells, plant cells and cells of aerobic bacteria. This enzyme converts hydrogen peroxide into water and oxygen gas, an exothermic reaction.
• urease; an enzyme belonging to the amidases or amide splitting enzymes. It breaks down urea, a waste product of protein metabolism. Urease (urea amidohydrolase) is an enzyme that catalyzes the hydrolysis of urea to carbon dioxide and ammonia,

An excessively high value of one or more of these factors always indicates a functionally unhealthy gut (dysbiosis).