Protein Spectrum Protein Electrophoresis and Protein Total

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Depending on the disease, differences in the composition of protein fractions occur. Protein electrophoresis is used to measure the different proteins.

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Protein Spectrum Protein Electrophoresis and Protein Total

In this test, protein electrophoresis and protein total (protein) from serum are determined.

Depending on the disease, differences in the composition of the protein fractions occur. protein electrophoresis is used to measure the different proteins. It also plays an important role in detecting monoclonal gammopathy. That is a condition in which certain antibodies, called immunoglobulins, are found in the blood or urine. Therefore, it is important to combine this test with immunoglobulin IgA, IgG and IgM.

This test is used for:

Monoclonal Gammopathy
Acute and chronic inflammatory reactions
Tumors
Liver Diseases
Protein loss (e.g. kidney problems)
Immune dysfunction
autoimmune diseases
fatigue in combination with bone fractures
Protein malnutrition
Problems with blood flow (e.g. sickle cell disease)
If previously measured protein total deviates

Examples of causes of deviations are

Type of protein	Lowered	Increased
Albumin	Malnutrition or poor dietary intake Pregnancy Kidney disease Liver Disease Inflammation	Dewatering
Alpha-1	Genetic anomaly Liver Disease	Inflammation
Alpha-2	Thyroid dysfunction Liver Disease Hemolysis Infection	Kidney Disease
Beta	Malnutrition Liver Disease Anemia	Hypercholesterolemia
Gamma	Genetic anomaly Impaired functioning of the immune system	Inflammation