MMA Methylmalonic Acid and Homocysteine in Blood
This test consists of Methylmalonic acid in blood (serum) and Homocysteine (NaF gray tube)
Methylmalonic acid is an organic acid that is usually elevated in B12 deficiency. If the normal B12 test does not provide clarity, this test can be done to clarify whether B12 deficiency is present.
Elevated serum levels of MMA are also found in people with renal insufficiency, hypovolemia (low circulating blood volume) and bacterial overgrowth in the intestines. Thus, in these cases, the value of MMA cannot be used to diagnose B12 deficiency, but of course a B12 deficiency may exist simultaneously. One can, however, test MMA in urine in kidney patients (and hypovolemic).
This test is should be kept refrigerated. Blood collection Monday through Thursday and send according to instructions provided. In summer, when it is hot, it is better to test MMA in urine.
Regarding homocysteine, you need to be sober for 12 hours before blood sampling for this test.
Do not send in in extremely hot weather and drop off at a PostNL service point on hot days, do not deposit in the mailbox. Store blood on early collection in the refrigerator on day of shipment.














