iGene DNA test Health Morbus Wilson saliva test
The iGene DNA test - Health with additional analysis for Wilson disease (morbus Wilson) is a comprehensive genetic test that not only provides insight into your personal predisposition to disease, drug susceptibility and genetic characteristics, but also looks specifically for mutations in the ATP7B gene. These mutations may indicate an increased risk of Wilson disease - an inherited condition in which copper accumulates in the liver and brain, among other areas.
In this variant, the morbus Wilson gene is analyzed and interpreted directly from the raw DNA data. An informed consent is required for this additional determination. This analysis can help in early detection of the disease, identifying carrier status or determining familial risk. In consultation with a clinician, other conditions may be temporarily excluded if necessary.
This DNA analysis offers insight into such topics as:
Genetic predisposition for morbus Wilson (ATP7B gene), among others.
Sensitivity to commonly used medications and personal pharmacogenetic profile
Personal genetic characteristics (such as lactose intolerance, taste perception, hair color)
Optional: genetic predisposition for 15 other conditions, coupled with lifestyle recommendations
You receive an iGene DNA kit at home that you use to submit a DNA sample via saliva collection. The analysis takes place in a medical laboratory. Within 4 to 6 weeks the results are available in the iGene App, as a downloadable PDF, and as raw data. You will also receive automatic updates via the message service as soon as there are new genetic insights.
Need help interpreting your results? Our iGene Certified Professionals are available for personalized guidance.
The results
Morbus Wilson analysis results contain information about specific mutations in the ATP7B gene. These results are important in detecting the disease or carrier status and can be shared with your doctor. You will also receive a comprehensive genetic profile via the iGene App and as a PDF report.
Do I need to be sober for this test?
No, this DNA test does not require you to be sober. You simply take the saliva sample at home using the included instructions.
What is Wilson's disease?
Wilson's disease (morbus Wilson) is an inherited disorder in which copper accumulates in the body. It is caused by mutations in the ATP7B gene, which leads to impaired disposal of copper. Diagnosis is often difficult, but genetic analysis can help confirm the condition or carrier status.
Why is a consent form required?
Because this is a genetic analysis with medical implications, it is required by law to obtain your consent before we analyze this particular mutation in the ATP7B gene. You will receive an informed consent form for this upon ordering.
Can I also choose not to see the other conditions temporarily?
Yes, if you coordinate with us in advance and enter our practitioner code, the other conditions can be disabled. You will still receive accompanying lifestyle recommendations.
What is the benefit of a DNA test like this?
A DNA test is not a snapshot, but a lifelong investment in your health. With one saliva sample, you gain insight into your genetic predisposition, with regular updates as science progresses.
What else is tested besides morbus Wilson?
The test includes drug sensitivity (including MTHFR and other enzymes), personal characteristics such as lactose intolerance or muscle building, and optionally 15 other conditions such as cardiovascular disease, type 2 diabetes, Alzheimer's and various cancers.
Can I discuss my result with a specialist?
Yes, you can request a consultation with an iGene Certified Professional. He or she will help you interpret your results and advise you on next steps or lifestyle changes.
