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  • Glucose-6-phosphate dehydrogenase

Glucose-6-phosphate dehydrogenase

    Glucose-6-phosphate dehydrogenase (erythrocyte) EDTA blood

    € 29,-

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    1265 reviews

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    James

    Great customer service!

    10/10

    Dex Hermans

    I am very satisfied with the company and regularly load my blood tests. The only pity is that you don't get a confirmation when the blood has arrived. That would be an added value...

    Product Description

    Glucose-6-phosphate dehydrogenase

    Blood tests Favism diagnostics G-6-PDH G6P-DH from EDTA.

    Broad bean disease or favism is an inherited disorder, localized on the X chromosome.

    The nosebleeds are part of it. You don't grow out of this.

    It is not an allergy but an enzyme defect. That is, your body does not produce enough of the G6PD enzymes to protect red blood cells from hemolysis (blood breakdown) when exposed to certain substances. There are at least 400 million people worldwide who have this inherited enzyme deficiency. There are different variants and classes depending on the gene mutation.

    Carbohydrate metabolism Rare congenital metabolic disorders

    To be requested in case of a suspected glucose-6-phosphate dehydrogenase deficiency in hemolytic anemia, aggravated in particular by infections, ingestion of food (broad beans) or after administration of medication (quinine, primaquine, chloroquine, sulfonamides, ASA, etc.).

    The main culprits in food are the substances vicin and convicin. They are mainly found in legumes, with the highest concentrations in broad beans. The list of medications and extensive information can be consulted (in English and Italian) on the website http://www.g6pd.org.

    Eating broad beans and a whole laundry list of medications (including aspirin) can trigger hemolysis. To date, there is no cure for this.

    Glucose-6-phosphate dehydrogenase deficiency is the most common human enzyme deficiency in the world; an estimated 400 million people suffer from it. G6PD deficiency is also known as "favism," because G6PD deficient individuals are somatically allergic to fava beans.

    G6PD deficiency is hereditary.

    The determined activity gives an indication of the presence of the disease. Reticulocyte count should be considered in the assessment, as an increased reticulocyte count may result in incorrectly high values.

    Guideline values
    6.6 - 17.2 E / g Hb
    Method
    Photometry (PHOT)

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