The test measures the total amount of protein in the blood. It includes the albumin/globulin quotient.
Proteins play an important role in the proper functioning of the body. The "total protein" test includes two major groups of proteins: albumin and globulins.
Albumin, the most abundant protein in the blood, provides transport of small molecules. In addition, the protein prevents water from leaking from blood vessels into surrounding tissues. Albumin deficiency can lead to edema (swelling) in which water accumulates in surrounding tissues.
Globulins are a very diverse group of proteins. It includes more than 500 different types including enzymes and antibodies (immunoglobulins). Many of these proteins are made in the liver.