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  • TSH Receptor Axis Graves' disease thyroid gland

TSH Receptor Axis Graves' disease thyroid gland

    € 57,-

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    • No referral needed from your family doctor
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    • Puncture points throughout the Netherlands

    1265 reviews

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    10/10

    James

    Great customer service!

    10/10

    Dex Hermans

    I am very satisfied with the company and regularly load my blood tests. The only pity is that you don't get a confirmation when the blood has arrived. That would be an added value...

    Product Description

    TSH Receptor Axis Graves' disease thyroid gland

    TSH receptor antibodies: Here, TSH-R a.s. (also called ThyrStimIg, TSI Thyreoid stim. IgG (TSI) ,TSH recept. al.) tested TRAK from serum.

    The test determines the presence of and TSH receptor antibodies to thyroid cells. Many thyroid diseases are caused by autoantibodies. These occur when the immune system mistakenly considers (components of) thyroid cells to be "foreign" (not native to the body) and creates antibodies to destroy these cells. They are called autoantibodies because the immune system acts against thyroid cells of its own. They can cause a variety of thyroid abnormalities, such as thyroiditis, damage to thyroid tissue and/or disruption of thyroid function.

    TSH receptor antibodies can have either a stimulatory or an inhibitory effect on the thyroid, but the stimulatory effect is by far the most common.

    With a thyroid that works too fast and the presence of and TSH receptor antibodies, these antibodies bind to the thyroid gland and cause excessive levels and FT4 in the blood. Symptoms that result include: palpitations, shortness of breath on exertion, heat discomfort, excessive sweating, nervousness and weight loss.

    When the thyroid gland is working too slowly, anti-TPO and antibodies are often found and it is called Hashimoto's disease.

    Symptoms of a slow-acting thyroid gland include:




    • fatigue
    • coldness
    • weight gain
    • dry skin
    • hair loss
    • lowering of the voice and constipation

    Table: Hormone and autoantibody characteristics in diagnosis of thyroid autoimmunity *.

    Graves' diseaseHashimoto's disease
    TSHreducedTSHincreased
    T4,T3,increasedT4, T3,reduced
    TSH receptor antibodies
    (mostly stimulating)
    80-100%TSH receptor antibodies
    (mostly blocking)
    6%
    TPO autoantibodies45-80%TPO autoantibodies (hightiter)95%
    Tg autoantibodies12-30%Tg autoantibodies (high titer)50-60%

    % within the patient population

     

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      TSH Receptor Axis Graves' disease thyroid gland

      TSH Receptor Axis Graves' disease thyroid gland

      € 57,-

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