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  • Factor II mutans gene mutation G20210A

Factor II mutans gene mutation G20210A

    Prothrombin mutation (Factor II polymorphism) (PCR)' 'EDTA blood


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    • No referral needed from your family doctor
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    • Puncture points throughout the Netherlands

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    Very nice agency. I have a full check done annually and am very satisfied. Result of the test comes quickly and customer service is easily accessible.



    Super fast, received results of extensive blood test after only one week

    Product Description

    Factor II mutans gene mutation G20210A

    Factor-II-Mutation (G20210A) (EDTA code PTMPC)

    This DNA test requires a consent form from your treating physician.

    Factor II (prothrombin) mutation

    this gene mutation occurs in 2 to 3% of the population The prothrombin mutation G20210A also a significant risk factor for the development of thrombosis. Unlike the factor V Leiden mutation, the prothrombin mutation is associated with both venous and arterial thrombosis.
    The exchange of guanine for adenine at position 20210 in the regulatory region of the prothrombin gene leads to increased expression of the gene and thus accumulation of the factor in the plasma, which in turn leads to an increase in blood clotting risk
    The mutation is usually present in a heterozygous form and is associated with a 2 to 3-fold increased risk of thrombosis. In the rare homozygous form, the risk of thrombosis probably increases 15 to 20 times. It is not uncommon for the prothrombin mutation and Factor V Leiden mutation to be present together.
    In women with a genetic predisposition (Factor V and/or prothrombin mutation), the risk of thrombosis may be 30 times higher.


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      Factor II mutans gene mutation G20210A

      Factor II mutans gene mutation G20210A

      € 169,-

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